C274-1564 Screening compound: ethyl 2-(2-{1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-amido}-1,3-thiazol-4-yl)acetate

C274-1564 Screening compound: ethyl 2-(2-{1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-amido}-1,3-thiazol-4-yl)acetate
C274-1564 Screening compound: ethyl 2-(2-{1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-amido}-1,3-thiazol-4-yl)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-1564
ethyl 2-(2-{1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-amido}-1,3-thiazol-4-yl)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-1564

Molecular Formula

C18H23N5O7S2 (C18 H23 N5 O7 S2)

Compound Name

ethyl 2-(2-{1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-amido}-1,3-thiazol-4-yl)acetate

IUPAC name

ethyl 2-(2-{1-[(6-methyl-24-dioxo-1234-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-amido}-13-thiazol-4-yl)acetate

SMILES

CCOC(Cc1csc(NC(C(CC2)CCN2S(C(C(N2)=O)=C(C)NC2=O)(=O)=O)=O)n1)=O

InChI

InChI=1S/C18H23N5O7S2/c1-3-30-13(24)8-12-9-31-18(20-12)22-15(25)11-4-6-23(7-5-11)32(28,29)14-10(2)19-17(27)21-16(14)26/h9,11H,3-8H2,1-2H3,(H,20,22,25)(H2,19,21,26,27)

InChI Key

GZOOBXKSILBPFA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14740221

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.54

Hydrogen Bond Acceptors Count

15.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

12

Partition Coefficient, logP

0.161

Distribution Coefficient, logD

-2.607

Water Solubility, LogSw

-2.14

Polar Surface Area

134.275

Acid Dissociation Constant (pKa)

4.63

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

C274-1564 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C274-1564 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-1564?
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What is the minimum amount of C274-1564 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-1564
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-1564
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-1564 available by request