C274-1569 Screening compound: 5-[(4-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}piperidin-1-yl)sulfonyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

C274-1569 Screening compound: 5-[(4-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}piperidin-1-yl)sulfonyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
C274-1569 Screening compound: 5-[(4-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}piperidin-1-yl)sulfonyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-1569
5-[(4-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}piperidin-1-yl)sulfonyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-1569

Molecular Formula

C23H29N5O7S (C23 H29 N5 O7 S)

Compound Name

5-[(4-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}piperidin-1-yl)sulfonyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

5-[(4-{4-[(2H-13-benzodioxol-5-yl)methyl]piperazine-1-carbonyl}piperidin-1-yl)sulfonyl]-6-methyl-1234-tetrahydropyrimidine-24-dione

SMILES

CC(NC(NC1=O)=O)=C1S(N(CC1)CCC1C(N1CCN(Cc(cc2)cc3c2OCO3)CC1)=O)(=O)=O

InChI

InChI=1S/C23H29N5O7S/c1-15-20(21(29)25-23(31)24-15)36(32,33)28-6-4-17(5-7-28)22(30)27-10-8-26(9-11-27)13-16-2-3-18-19(12-16)35-14-34-18/h2-3,12,17H,4-11,13-14H2,1H3,(H2,24,25,29,31)

InChI Key

OEZUVQWOTNYOIN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14740223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

519.58

Hydrogen Bond Acceptors Count

14.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

12

Partition Coefficient, logP

-0.033

Distribution Coefficient, logD

-0.033

Water Solubility, LogSw

-2.59

Polar Surface Area

117.788

Acid Dissociation Constant (pKa)

4.63

Base Dissociation Constant (pKb)

7.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

C274-1569 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleoside Mimetics Library (2197 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Cancer
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
Structure:
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C274-1569 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-1569?
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What is the minimum amount of C274-1569 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-1569
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-1569
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-1569 available by request