C274-2777 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide

C274-2777 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide
C274-2777 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-2777
1-[(5-bromothiophen-2-yl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-2777

Molecular Formula

C14H16BrN3O3S3 (C14 H16 BrN3 O3 S3)

Compound Name

1-[(5-bromothiophen-2-yl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)piperidine-3-carboxamide

IUPAC name

1-[(5-bromothiophen-2-yl)sulfonyl]-N-(4-methyl-13-thiazol-2-yl)piperidine-3-carboxamide

SMILES

Cc1csc(NC(C(CCC2)CN2S(c(s2)ccc2Br)(=O)=O)=O)n1

InChI

InChI=1S/C14H16BrN3O3S3/c1-9-8-22-14(16-9)17-13(19)10-3-2-6-18(7-10)24(20,21)12-5-4-11(15)23-12/h4-5,8,10H,2-3,6-7H2,1H3,(H,16,17,19)/t10-/m0/s1

InChI Key

PYKSRSIOMWAHKC-JTQLQIEISA-N

MDL Number (MFCD)

MFCD05027363

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.929

Distribution Coefficient, logD

2.810

Water Solubility, LogSw

-3.29

Polar Surface Area

65.845

Acid Dissociation Constant (pKa)

7.90

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

C274-2777 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with C274-2777 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-2777?
Check Price and Availability of C274-2777, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C274-2777 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-2777
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-2777
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-2777 available by request