C274-8080 Screening compound: N-(2,5-dimethoxyphenyl)-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

C274-8080 Screening compound: N-(2,5-dimethoxyphenyl)-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide
C274-8080 Screening compound: N-(2,5-dimethoxyphenyl)-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-8080
N-(2,5-dimethoxyphenyl)-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-8080

Molecular Formula

C19H24N4O7S (C19 H24 N4 O7 S)

Compound Name

N-(2,5-dimethoxyphenyl)-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-(25-dimethoxyphenyl)-1-[(6-methyl-24-dioxo-1234-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CC(NC(NC1=O)=O)=C1S(N(CCC1)CC1C(Nc(cc(cc1)OC)c1OC)=O)(=O)=O

InChI

InChI=1S/C19H24N4O7S/c1-11-16(18(25)22-19(26)20-11)31(27,28)23-8-4-5-12(10-23)17(24)21-14-9-13(29-2)6-7-15(14)30-3/h6-7,9,12H,4-5,8,10H2,1-3H3,(H,21,24)(H2,20,22,25,26)/t12-/m0/s1

InChI Key

ABJSLMSOFFLYGI-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD14740476

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.49

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

0.076

Distribution Coefficient, logD

-2.692

Water Solubility, LogSw

-2.43

Polar Surface Area

117.985

Acid Dissociation Constant (pKa)

4.63

Base Dissociation Constant (pKb)

0.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.10

C274-8080 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C274-8080 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-8080?
Check Price and Availability of C274-8080, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C274-8080 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-8080
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-8080
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-8080 available by request