C276-0363 Screening compound: 8-(3-chloro-5-ethoxy-4-hydroxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one

C276-0363 Screening compound: 8-(3-chloro-5-ethoxy-4-hydroxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one
C276-0363 Screening compound: 8-(3-chloro-5-ethoxy-4-hydroxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C276-0363
8-(3-chloro-5-ethoxy-4-hydroxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C276-0363

Molecular Formula

C18H16ClNO5 (C18 H16 ClNO5)

Compound Name

8-(3-chloro-5-ethoxy-4-hydroxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one

IUPAC name

8-(3-chloro-5-ethoxy-4-hydroxyphenyl)-2H5H6H7H8H-[13]dioxolo[45-g]quinolin-6-one

SMILES

CCOc1cc(C(C2)c(cc3OCOc3c3)c3NC2=O)cc(Cl)c1O

InChI

InChI=1S/C18H16ClNO5/c1-2-23-16-4-9(3-12(19)18(16)22)10-6-17(21)20-13-7-15-14(5-11(10)13)24-8-25-15/h3-5,7,10,22H,2,6,8H2,1H3,(H,20,21)/t10-/m0/s1

InChI Key

ISRVSNHKHFDJGQ-JTQLQIEISA-N

MDL Number (MFCD)

MFCD06005462

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.78

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.586

Distribution Coefficient, logD

3.555

Water Solubility, LogSw

-3.51

Polar Surface Area

64.593

Acid Dissociation Constant (pKa)

8.54

Base Dissociation Constant (pKb)

-0.23

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.80

C276-0363 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cardiovascular

References: we are preparing a list of scientific research reports with C276-0363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C276-0363?
Check Price and Availability of C276-0363, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C276-0363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C276-0363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C276-0363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C276-0363 available by request