C276-0486 Screening compound: 8-(5-chloro-2-ethoxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one

C276-0486 Screening compound: 8-(5-chloro-2-ethoxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one
C276-0486 Screening compound: 8-(5-chloro-2-ethoxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C276-0486
8-(5-chloro-2-ethoxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C276-0486

Molecular Formula

C18H16ClNO4 (C18 H16 ClNO4)

Compound Name

8-(5-chloro-2-ethoxyphenyl)-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one

IUPAC name

8-(5-chloro-2-ethoxyphenyl)-2H5H6H7H8H-[13]dioxolo[45-g]quinolin-6-one

SMILES

CCOc(cc1)c(C(C2)c(cc3OCOc3c3)c3NC2=O)cc1Cl

InChI

InChI=1S/C18H16ClNO4/c1-2-22-15-4-3-10(19)5-13(15)11-7-18(21)20-14-8-17-16(6-12(11)14)23-9-24-17/h3-6,8,11H,2,7,9H2,1H3,(H,20,21)/t11-/m0/s1

InChI Key

ZGNPIRLGZNIEBK-NSHDSACASA-N

MDL Number (MFCD)

MFCD06007903

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.78

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.786

Distribution Coefficient, logD

3.786

Water Solubility, LogSw

-4.06

Polar Surface Area

49.113

Acid Dissociation Constant (pKa)

11.12

Base Dissociation Constant (pKb)

-0.74

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.80

C276-0486 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Cardiovascular Library (22201 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cardiovascular
  • Infections
  • Immune system
  • animal
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C276-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C276-0486?
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What is the minimum amount of C276-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C276-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C276-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C276-0486 available by request