C282-0010 Screening compound: 3-[4-(4-methoxyphenyl)-6,8-dimethyl-2-(4-methylpiperidino)pyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid

C282-0010 Screening compound: 3-[4-(4-methoxyphenyl)-6,8-dimethyl-2-(4-methylpiperidino)pyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid
C282-0010 Screening compound: 3-[4-(4-methoxyphenyl)-6,8-dimethyl-2-(4-methylpiperidino)pyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound C282-0010
3-[4-(4-methoxyphenyl)-6,8-dimethyl-2-(4-methylpiperidino)pyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C282-0010

Molecular Formula

C26H30N6O3 (C26 H30 N6 O3)

Compound Name

3-[4-(4-methoxyphenyl)-6,8-dimethyl-2-(4-methylpiperidino)pyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid

IUPAC name

3-[13-(4-methoxyphenyl)-46-dimethyl-11-(4-methylpiperidin-1-yl)-3781012-pentaazatricyclo[7.4.0.0^{27}]trideca-13581012-hexaen-5-yl]propanoic acid

SMILES

CC(CC1)CCN1c1nc2nn3c(C)c(CCC(O)=O)c(C)nc3c2c(-c(cc2)ccc2OC)n1

InChI

InChI=1S/C26H30N6O3/c1-15-11-13-31(14-12-15)26-28-23(18-5-7-19(35-4)8-6-18)22-24(29-26)30-32-17(3)20(9-10-21(33)34)16(2)27-25(22)32/h5-8,15H,9-14H2,1-4H3,(H,33,34)

InChI Key

TWOKPULFYJZXRU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03829957

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.448

Distribution Coefficient, logD

1.621

Water Solubility, LogSw

-4.55

Polar Surface Area

78.957

Acid Dissociation Constant (pKa)

4.57

Base Dissociation Constant (pKb)

3.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

C282-0010 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Integrin Receptors Targeted library (1715 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C282-0010 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C282-0010?
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What is the minimum amount of C282-0010 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C282-0010
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C282-0010
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C282-0010 available by request