C284-0296 Screening compound: 3-(2,4-dimethoxyphenyl)-6-nitro-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-3,4-dihydroquinazolin-4-one

C284-0296 Screening compound: 3-(2,4-dimethoxyphenyl)-6-nitro-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-3,4-dihydroquinazolin-4-one
C284-0296 Screening compound: 3-(2,4-dimethoxyphenyl)-6-nitro-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C284-0296
3-(2,4-dimethoxyphenyl)-6-nitro-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C284-0296

Molecular Formula

C26H26N6O5 (C26 H26 N6 O5)

Compound Name

3-(2,4-dimethoxyphenyl)-6-nitro-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-3,4-dihydroquinazolin-4-one

IUPAC name

3-(24-dimethoxyphenyl)-6-nitro-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-34-dihydroquinazolin-4-one

SMILES

COc(cc1)cc(OC)c1N(C(CN(CC1)CCN1c1ncccc1)=Nc(cc1)c2cc1[N+]([O-])=O)C2=O

InChI

InChI=1S/C26H26N6O5/c1-36-19-7-9-22(23(16-19)37-2)31-25(28-21-8-6-18(32(34)35)15-20(21)26(31)33)17-29-11-13-30(14-12-29)24-5-3-4-10-27-24/h3-10,15-16H,11-14,17H2,1-2H3

InChI Key

SVFPEUPDDMTXJS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14740781

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

502.53

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

2.866

Distribution Coefficient, logD

2.845

Water Solubility, LogSw

-3.47

Polar Surface Area

88.625

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

6.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

C284-0296 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C284-0296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C284-0296?
Check Price and Availability of C284-0296, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C284-0296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C284-0296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C284-0296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C284-0296 available by request