C284-0424 Screening compound: 3-(2-fluorophenyl)-2-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-6-nitro-3,4-dihydroquinazolin-4-one

C284-0424 Screening compound: 3-(2-fluorophenyl)-2-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-6-nitro-3,4-dihydroquinazolin-4-one
C284-0424 Screening compound: 3-(2-fluorophenyl)-2-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-6-nitro-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C284-0424
3-(2-fluorophenyl)-2-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-6-nitro-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C284-0424

Molecular Formula

C25H21F2N5O3 (C25 H21 F2 N5 O3)

Compound Name

3-(2-fluorophenyl)-2-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-6-nitro-3,4-dihydroquinazolin-4-one

IUPAC name

3-(2-fluorophenyl)-2-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-6-nitro-34-dihydroquinazolin-4-one

SMILES

[O-][N+](c(cc1)cc2c1N=C(CN(CC1)CCN1c(cccc1)c1F)N(c(cccc1)c1F)C2=O)=O

InChI

InChI=1S/C25H21F2N5O3/c26-19-5-1-3-7-22(19)30-13-11-29(12-14-30)16-24-28-21-10-9-17(32(34)35)15-18(21)25(33)31(24)23-8-4-2-6-20(23)27/h1-10,15H,11-14,16H2

InChI Key

VWVLVAZNAMZTNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14740816

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.342

Distribution Coefficient, logD

3.342

Water Solubility, LogSw

-3.84

Polar Surface Area

64.638

Acid Dissociation Constant (pKa)

20.43

Base Dissociation Constant (pKb)

2.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

C284-0424 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C284-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C284-0424?
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What is the minimum amount of C284-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C284-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C284-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C284-0424 available by request