C301-7463 Screening compound: 1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-2-oxo-2H-chromen-3-yl)urea

C301-7463 Screening compound: 1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-2-oxo-2H-chromen-3-yl)urea
C301-7463 Screening compound: 1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-2-oxo-2H-chromen-3-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound C301-7463
1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-2-oxo-2H-chromen-3-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C301-7463

Molecular Formula

C18H16N2O6 (C18 H16 N2 O6)

Compound Name

1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-2-oxo-2H-chromen-3-yl)urea

IUPAC name

1-(25-dimethoxyphenyl)-3-(4-hydroxy-2-oxo-2H-chromen-3-yl)urea

SMILES

COc(cc1)cc(NC(NC(C(Oc2c3cccc2)=O)=C3O)=O)c1OC

InChI

InChI=1S/C18H16N2O6/c1-24-10-7-8-14(25-2)12(9-10)19-18(23)20-15-16(21)11-5-3-4-6-13(11)26-17(15)22/h3-9,21H,1-2H3,(H2,19,20,23)

InChI Key

PJUANBCJAXMAFS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14744946

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.33

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.975

Distribution Coefficient, logD

-1.598

Water Solubility, LogSw

-2.95

Polar Surface Area

83.210

Acid Dissociation Constant (pKa)

3.40

Base Dissociation Constant (pKb)

3.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

C301-7463 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Others
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C301-7463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C301-7463?
Check Price and Availability of C301-7463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C301-7463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C301-7463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C301-7463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C301-7463 available by request