C301-8448 Screening compound: 1,3-dimethyl 5-[3-(morpholin-4-yl)quinoxaline-2-amido]benzene-1,3-dicarboxylate

C301-8448 Screening compound: 1,3-dimethyl 5-[3-(morpholin-4-yl)quinoxaline-2-amido]benzene-1,3-dicarboxylate
C301-8448 Screening compound: 1,3-dimethyl 5-[3-(morpholin-4-yl)quinoxaline-2-amido]benzene-1,3-dicarboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound C301-8448
1,3-dimethyl 5-[3-(morpholin-4-yl)quinoxaline-2-amido]benzene-1,3-dicarboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C301-8448

Molecular Formula

C23H22N4O6 (C23 H22 N4 O6)

Compound Name

1,3-dimethyl 5-[3-(morpholin-4-yl)quinoxaline-2-amido]benzene-1,3-dicarboxylate

IUPAC name

13-dimethyl 5-[3-(morpholin-4-yl)quinoxaline-2-amido]benzene-13-dicarboxylate

SMILES

COC(c1cc(C(OC)=O)cc(NC(c2nc3ccccc3nc2N2CCOCC2)=O)c1)=O

InChI

InChI=1S/C23H22N4O6/c1-31-22(29)14-11-15(23(30)32-2)13-16(12-14)24-21(28)19-20(27-7-9-33-10-8-27)26-18-6-4-3-5-17(18)25-19/h3-6,11-13H,7-10H2,1-2H3,(H,24,28)

InChI Key

ODQUSRXSMTUZOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14745445

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.45

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.871

Distribution Coefficient, logD

3.866

Water Solubility, LogSw

-4.08

Polar Surface Area

94.675

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

1.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

C301-8448 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C301-8448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C301-8448?
Check Price and Availability of C301-8448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C301-8448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C301-8448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C301-8448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C301-8448 available by request