C324-1458 Screening compound: [4-(2-CHLOROPHENYL)PIPERAZINO]{1-[(3,5-DIMETHYL-4-ISOXAZOLYL)SULFONYL]-4-PIPERIDYL}METHANONE

C324-1458 Screening compound: [4-(2-CHLOROPHENYL)PIPERAZINO]{1-[(3,5-DIMETHYL-4-ISOXAZOLYL)SULFONYL]-4-PIPERIDYL}METHANONE
C324-1458 Screening compound: [4-(2-CHLOROPHENYL)PIPERAZINO]{1-[(3,5-DIMETHYL-4-ISOXAZOLYL)SULFONYL]-4-PIPERIDYL}METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound C324-1458
[4-(2-CHLOROPHENYL)PIPERAZINO]{1-[(3,5-DIMETHYL-4-ISOXAZOLYL)SULFONYL]-4-PIPERIDYL}METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C324-1458

Molecular Formula

C21H27ClN4O4S (C21 H27 ClN4 O4 S)

Compound Name

[4-(2-CHLOROPHENYL)PIPERAZINO]{1-[(3,5-DIMETHYL-4-ISOXAZOLYL)SULFONYL]-4-PIPERIDYL}METHANONE

IUPAC name

n/a

SMILES

Cc1noc(C)c1S(N(CC1)CCC1C(N(CC1)CCN1c(cccc1)c1Cl)=O)(=O)=O

InChI

InChI=1S/C21H27ClN4O4S/c1-15-20(16(2)30-23-15)31(28,29)26-9-7-17(8-10-26)21(27)25-13-11-24(12-14-25)19-6-4-3-5-18(19)22/h3-6,17H,7-14H2,1-2H3

InChI Key

REFFMIHHDTZWMH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14748518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.99

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.367

Distribution Coefficient, logD

2.367

Water Solubility, LogSw

-2.86

Polar Surface Area

73.595

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

2.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

C324-1458 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

GPCR Targeted Library (31838 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C324-1458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C324-1458?
Check Price and Availability of C324-1458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C324-1458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C324-1458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C324-1458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C324-1458 available by request