C325-0459 Screening compound: N-(4-chlorophenyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-amine

C325-0459 Screening compound: N-(4-chlorophenyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-amine
C325-0459 Screening compound: N-(4-chlorophenyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound C325-0459
N-(4-chlorophenyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C325-0459

Molecular Formula

C18H12ClFN4 (C18 H12 ClFN4)

Compound Name

N-(4-chlorophenyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-amine

IUPAC name

N-(4-chlorophenyl)-2-(4-fluorophenyl)imidazo[12-a]pyrimidin-3-amine

SMILES

Fc(cc1)ccc1-c1c(Nc(cc2)ccc2Cl)n(cccn2)c2n1

InChI

InChI=1S/C18H12ClFN4/c19-13-4-8-15(9-5-13)22-17-16(12-2-6-14(20)7-3-12)23-18-21-10-1-11-24(17)18/h1-11,22H

InChI Key

HZYPVHXQSBNZAE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09694808

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.77

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.100

Distribution Coefficient, logD

4.098

Water Solubility, LogSw

-4.71

Polar Surface Area

28.155

Acid Dissociation Constant (pKa)

17.95

Base Dissociation Constant (pKb)

5.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

C325-0459 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antifungal Library (16415 compounds)

C-Met Library (15277 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Agro:
  • Agro
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with C325-0459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C325-0459?
Check Price and Availability of C325-0459, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C325-0459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C325-0459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C325-0459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C325-0459 available by request