C325-0463 Screening compound: 4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-2-yl}phenol

C325-0463 Screening compound: 4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-2-yl}phenol
C325-0463 Screening compound: 4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C325-0463
4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C325-0463

Molecular Formula

C20H17BrN4O3 (C20 H17 BrN4 O3)

Compound Name

4-bromo-2-{3-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-2-yl}phenol

IUPAC name

4-bromo-2-{3-[(34-dimethoxyphenyl)amino]imidazo[12-a]pyrimidin-2-yl}phenol

SMILES

COc(ccc(Nc1c(-c(cc(cc2)Br)c2O)nc2ncccn12)c1)c1OC

InChI

InChI=1S/C20H17BrN4O3/c1-27-16-7-5-13(11-17(16)28-2)23-19-18(14-10-12(21)4-6-15(14)26)24-20-22-8-3-9-25(19)20/h3-11,23,26H,1-2H3

InChI Key

ODEGSKVLIIZEAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682867

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.28

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.170

Distribution Coefficient, logD

4.145

Water Solubility, LogSw

-3.99

Polar Surface Area

59.964

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

5.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

C325-0463 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with C325-0463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C325-0463?
Check Price and Availability of C325-0463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C325-0463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C325-0463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C325-0463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C325-0463 available by request