C340-0401 Screening compound: 1-[2-(4-chlorophenyl)ethyl]-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]thiourea

C340-0401 Screening compound: 1-[2-(4-chlorophenyl)ethyl]-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]thiourea
C340-0401 Screening compound: 1-[2-(4-chlorophenyl)ethyl]-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]thiourea alternative view

Chemical Structure Depiction of ChemDiv screening compound C340-0401
1-[2-(4-chlorophenyl)ethyl]-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]thiourea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C340-0401

Molecular Formula

C23H25ClN4OS (C23 H25 ClN4 OS)

Compound Name

1-[2-(4-chlorophenyl)ethyl]-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]thiourea

IUPAC name

1-[2-(4-chlorophenyl)ethyl]-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]thiourea

SMILES

Cc1c(cc(cc2)NC(NCCc(cc3)ccc3Cl)=S)c2nc(N2CCOCC2)c1

InChI

InChI=1S/C23H25ClN4OS/c1-16-14-22(28-10-12-29-13-11-28)27-21-7-6-19(15-20(16)21)26-23(30)25-9-8-17-2-4-18(24)5-3-17/h2-7,14-15H,8-13H2,1H3,(H2,25,26,30)

InChI Key

HKJNKUYNWRTEJX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14749904

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.173

Distribution Coefficient, logD

5.173

Water Solubility, LogSw

-5.58

Polar Surface Area

39.380

Acid Dissociation Constant (pKa)

13.04

Base Dissociation Constant (pKb)

4.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

C340-0401 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C340-0401 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C340-0401?
Check Price and Availability of C340-0401, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C340-0401 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C340-0401
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C340-0401
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C340-0401 available by request