C350-0460 Screening compound: ethyl 2-[8-methyl-3-(4-methylphenyl)-1H-pyrazolo[4,3-c]quinolin-1-yl]acetate

C350-0460 Screening compound: ethyl 2-[8-methyl-3-(4-methylphenyl)-1H-pyrazolo[4,3-c]quinolin-1-yl]acetate
C350-0460 Screening compound: ethyl 2-[8-methyl-3-(4-methylphenyl)-1H-pyrazolo[4,3-c]quinolin-1-yl]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound C350-0460
ethyl 2-[8-methyl-3-(4-methylphenyl)-1H-pyrazolo[4,3-c]quinolin-1-yl]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C350-0460

Molecular Formula

C22H21N3O2 (C22 H21 N3 O2)

Compound Name

ethyl 2-[8-methyl-3-(4-methylphenyl)-1H-pyrazolo[4,3-c]quinolin-1-yl]acetate

IUPAC name

ethyl 2-[8-methyl-3-(4-methylphenyl)-1H-pyrazolo[43-c]quinolin-1-yl]acetate

SMILES

CCOC(Cn(c1c2cnc3ccc(C)cc13)nc2-c1ccc(C)cc1)=O

InChI

InChI=1S/C22H21N3O2/c1-4-27-20(26)13-25-22-17-11-15(3)7-10-19(17)23-12-18(22)21(24-25)16-8-5-14(2)6-9-16/h5-12H,4,13H2,1-3H3

InChI Key

FTWXDBLDQSFNSS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14750425

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.624

Distribution Coefficient, logD

4.620

Water Solubility, LogSw

-4.12

Polar Surface Area

43.004

Acid Dissociation Constant (pKa)

22.84

Base Dissociation Constant (pKb)

5.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

C350-0460 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C350-0460 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C350-0460?
Check Price and Availability of C350-0460, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C350-0460 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C350-0460
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C350-0460
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C350-0460 available by request