C358-0175 Screening compound: 13-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-5-one

C358-0175 Screening compound: 13-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-5-one
C358-0175 Screening compound: 13-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C358-0175
13-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C358-0175

Molecular Formula

C32H35N3O4 (C32 H35 N3 O4)

Compound Name

13-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-2,3-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-5-one

IUPAC name

13-[4-(23-dimethylphenyl)piperazine-1-carbonyl]-23-dimethoxy-7812b13-tetrahydro-5H-6-azatetraphen-5-one

SMILES

Cc1cccc(N(CC2)CCN2C(C(C2N3CCc4c2cccc4)c(cc(c(OC)c2)OC)c2C3=O)=O)c1C

InChI

InChI=1S/C32H35N3O4/c1-20-8-7-11-26(21(20)2)33-14-16-34(17-15-33)32(37)29-24-18-27(38-3)28(39-4)19-25(24)31(36)35-13-12-22-9-5-6-10-23(22)30(29)35/h5-11,18-19,29-30H,12-17H2,1-4H3

InChI Key

OIYOHIZTKWADQN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14752429

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

525.65

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.914

Distribution Coefficient, logD

4.914

Water Solubility, LogSw

-4.60

Polar Surface Area

50.815

Acid Dissociation Constant (pKa)

12.66

Base Dissociation Constant (pKb)

5.28

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

37.50

C358-0175 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C358-0175 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C358-0175?
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What is the minimum amount of C358-0175 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C358-0175
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C358-0175
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C358-0175 available by request