C387-0347 Screening compound: 4-(4-benzylpiperazine-1-carbonyl)-N-(2,4-dimethoxyphenyl)quinolin-2-amine

C387-0347 Screening compound: 4-(4-benzylpiperazine-1-carbonyl)-N-(2,4-dimethoxyphenyl)quinolin-2-amine
C387-0347 Screening compound: 4-(4-benzylpiperazine-1-carbonyl)-N-(2,4-dimethoxyphenyl)quinolin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound C387-0347
4-(4-benzylpiperazine-1-carbonyl)-N-(2,4-dimethoxyphenyl)quinolin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C387-0347

Molecular Formula

C29H30N4O3 (C29 H30 N4 O3)

Compound Name

4-(4-benzylpiperazine-1-carbonyl)-N-(2,4-dimethoxyphenyl)quinolin-2-amine

IUPAC name

4-(4-benzylpiperazine-1-carbonyl)-N-(24-dimethoxyphenyl)quinolin-2-amine

SMILES

COc(cc1)cc(OC)c1Nc1nc2ccccc2c(C(N2CCN(Cc3ccccc3)CC2)=O)c1

InChI

InChI=1S/C29H30N4O3/c1-35-22-12-13-26(27(18-22)36-2)31-28-19-24(23-10-6-7-11-25(23)30-28)29(34)33-16-14-32(15-17-33)20-21-8-4-3-5-9-21/h3-13,18-19H,14-17,20H2,1-2H3,(H,30,31)

InChI Key

BGCSCNBHJCPMTQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14755391

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.961

Distribution Coefficient, logD

4.905

Water Solubility, LogSw

-4.83

Polar Surface Area

52.714

Acid Dissociation Constant (pKa)

18.63

Base Dissociation Constant (pKb)

6.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.10

C387-0347 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C387-0347 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C387-0347?
Check Price and Availability of C387-0347, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C387-0347 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C387-0347
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C387-0347
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C387-0347 available by request