C436-1035 Screening compound: 1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-3-piperidinecarboxamide

C436-1035 Screening compound: 1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-3-piperidinecarboxamide
C436-1035 Screening compound: 1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C436-1035
1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C436-1035

Molecular Formula

C18H21F3N4O3S (C18 H21 F3 N4 O3 S)

Compound Name

1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-[4-(trifluoromethyl)phenyl]-3-piperidinecarboxamide

IUPAC name

n/a

SMILES

Cc([nH]nc1C)c1S(N(CCC1)CC1C(Nc1ccc(C(F)(F)F)cc1)=O)(=O)=O

InChI

InChI=1S/C18H21F3N4O3S/c1-11-16(12(2)24-23-11)29(27,28)25-9-3-4-13(10-25)17(26)22-15-7-5-14(6-8-15)18(19,20)21/h5-8,13H,3-4,9-10H2,1-2H3,(H,22,26)(H,23,24)/t13-/m0/s1

InChI Key

WEHRLXSRNDGFJZ-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD14757819

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.199

Distribution Coefficient, logD

2.199

Water Solubility, LogSw

-2.74

Polar Surface Area

78.889

Acid Dissociation Constant (pKa)

11.33

Base Dissociation Constant (pKb)

-1.77

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.44

C436-1035 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C436-1035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C436-1035?
Check Price and Availability of C436-1035, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C436-1035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C436-1035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C436-1035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C436-1035 available by request