C450-0303 Screening compound: 2-(1-ACETYL-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDO)-N-(5-METHYLPYRIDIN-2-YL)-3-PHENYLPROPANAMIDE

C450-0303 Screening compound: 2-(1-ACETYL-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDO)-N-(5-METHYLPYRIDIN-2-YL)-3-PHENYLPROPANAMIDE
C450-0303 Screening compound: 2-(1-ACETYL-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDO)-N-(5-METHYLPYRIDIN-2-YL)-3-PHENYLPROPANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound C450-0303
2-(1-ACETYL-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDO)-N-(5-METHYLPYRIDIN-2-YL)-3-PHENYLPROPANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C450-0303

Molecular Formula

C25H26N4O4S (C25 H26 N4 O4 S)

Compound Name

2-(1-ACETYL-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDO)-N-(5-METHYLPYRIDIN-2-YL)-3-PHENYLPROPANAMIDE

IUPAC name

n/a

SMILES

CC(N(CC1)c(cc2)c1cc2S(NC(Cc1ccccc1)C(Nc1ncc(C)cc1)=O)(=O)=O)=O

InChI

InChI=1S/C25H26N4O4S/c1-17-8-11-24(26-16-17)27-25(31)22(14-19-6-4-3-5-7-19)28-34(32,33)21-9-10-23-20(15-21)12-13-29(23)18(2)30/h3-11,15-16,22,28H,12-14H2,1-2H3,(H,26,27,31)/t22-/m0/s1

InChI Key

OGSWUWIIOJBZJA-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD14759359

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.665

Distribution Coefficient, logD

3.657

Water Solubility, LogSw

-3.82

Polar Surface Area

91.055

Acid Dissociation Constant (pKa)

9.14

Base Dissociation Constant (pKb)

3.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

C450-0303 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SH2 Library (10483 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
  • GPCR
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C450-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C450-0303?
Check Price and Availability of C450-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C450-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C450-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C450-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C450-0303 available by request