C488-0397 Screening compound: 2-methoxy-4-{8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl}phenol

C488-0397 Screening compound: 2-methoxy-4-{8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl}phenol
C488-0397 Screening compound: 2-methoxy-4-{8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C488-0397
2-methoxy-4-{8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C488-0397

Molecular Formula

C22H21N3O2 (C22 H21 N3 O2)

Compound Name

2-methoxy-4-{8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl}phenol

IUPAC name

2-methoxy-4-{8-methyl-3-[(4-methylphenyl)amino]imidazo[12-a]pyridin-2-yl}phenol

SMILES

Cc(cc1)ccc1Nc1c(-c(cc2)cc(OC)c2O)nc2n1cccc2C

InChI

InChI=1S/C22H21N3O2/c1-14-6-9-17(10-7-14)23-22-20(16-8-11-18(26)19(13-16)27-3)24-21-15(2)5-4-12-25(21)22/h4-13,23,26H,1-3H3

InChI Key

USRBAKCJAMEJKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14761678

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.668

Distribution Coefficient, logD

3.837

Water Solubility, LogSw

-4.13

Polar Surface Area

42.404

Acid Dissociation Constant (pKa)

8.99

Base Dissociation Constant (pKb)

8.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

C488-0397 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C488-0397 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C488-0397?
Check Price and Availability of C488-0397, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C488-0397 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C488-0397
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C488-0397
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C488-0397 available by request