C488-1149 Screening compound: 4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-5-methylimidazo[1,2-a]pyridin-2-yl}phenol

C488-1149 Screening compound: 4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-5-methylimidazo[1,2-a]pyridin-2-yl}phenol
C488-1149 Screening compound: 4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-5-methylimidazo[1,2-a]pyridin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C488-1149
4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-5-methylimidazo[1,2-a]pyridin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C488-1149

Molecular Formula

C22H19N3O3 (C22 H19 N3 O3)

Compound Name

4-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-5-methylimidazo[1,2-a]pyridin-2-yl}phenol

IUPAC name

4-{3-[(23-dihydro-14-benzodioxin-6-yl)amino]-5-methylimidazo[12-a]pyridin-2-yl}phenol

SMILES

Cc1cccc2nc(-c(cc3)ccc3O)c(Nc(cc3)cc4c3OCCO4)n12

InChI

InChI=1S/C22H19N3O3/c1-14-3-2-4-20-24-21(15-5-8-17(26)9-6-15)22(25(14)20)23-16-7-10-18-19(13-16)28-12-11-27-18/h2-10,13,23,26H,11-12H2,1H3

InChI Key

NGHYBIRSZYVWHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682481

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.260

Distribution Coefficient, logD

3.242

Water Solubility, LogSw

-3.13

Polar Surface Area

50.763

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

C488-1149 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C488-1149 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C488-1149?
Check Price and Availability of C488-1149, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C488-1149 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C488-1149
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C488-1149
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C488-1149 available by request