C488-1435 Screening compound: 4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}phenol

C488-1435 Screening compound: 4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}phenol
C488-1435 Screening compound: 4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C488-1435
4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C488-1435

Molecular Formula

C21H16ClN3O3 (C21 H16 ClN3 O3)

Compound Name

4-{6-chloro-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]imidazo[1,2-a]pyridin-2-yl}phenol

IUPAC name

4-{6-chloro-3-[(23-dihydro-14-benzodioxin-6-yl)amino]imidazo[12-a]pyridin-2-yl}phenol

SMILES

Oc(cc1)ccc1-c1c(Nc(cc2)cc3c2OCCO3)n(cc(cc2)Cl)c2n1

InChI

InChI=1S/C21H16ClN3O3/c22-14-3-8-19-24-20(13-1-5-16(26)6-2-13)21(25(19)12-14)23-15-4-7-17-18(11-15)28-10-9-27-17/h1-8,11-12,23,26H,9-10H2

InChI Key

UMMMQPSDPMZUED-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682497

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.83

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.774

Distribution Coefficient, logD

3.767

Water Solubility, LogSw

-4.25

Polar Surface Area

51.012

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

C488-1435 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antifungal Library (16415 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C488-1435 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C488-1435?
Check Price and Availability of C488-1435, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C488-1435 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C488-1435
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C488-1435
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C488-1435 available by request