C488-1456 Screening compound: 6-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(5-methylthiophen-2-yl)imidazo[1,2-a]pyridin-3-amine

C488-1456 Screening compound: 6-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(5-methylthiophen-2-yl)imidazo[1,2-a]pyridin-3-amine
C488-1456 Screening compound: 6-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(5-methylthiophen-2-yl)imidazo[1,2-a]pyridin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound C488-1456
6-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(5-methylthiophen-2-yl)imidazo[1,2-a]pyridin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C488-1456

Molecular Formula

C20H16ClN3O2S (C20 H16 ClN3 O2 S)

Compound Name

6-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(5-methylthiophen-2-yl)imidazo[1,2-a]pyridin-3-amine

IUPAC name

6-chloro-N-(23-dihydro-14-benzodioxin-6-yl)-2-(5-methylthiophen-2-yl)imidazo[12-a]pyridin-3-amine

SMILES

Cc1ccc(-c2c(Nc(cc3)cc4c3OCCO4)n(cc(cc3)Cl)c3n2)s1

InChI

InChI=1S/C20H16ClN3O2S/c1-12-2-6-17(27-12)19-20(24-11-13(21)3-7-18(24)23-19)22-14-4-5-15-16(10-14)26-9-8-25-15/h2-7,10-11,22H,8-9H2,1H3

InChI Key

QXTRMNGALGHQBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682501

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.88

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.959

Distribution Coefficient, logD

4.954

Water Solubility, LogSw

-4.91

Polar Surface Area

34.413

Acid Dissociation Constant (pKa)

20.62

Base Dissociation Constant (pKb)

5.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

C488-1456 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Annotated Library (21441 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with C488-1456 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C488-1456?
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What is the minimum amount of C488-1456 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C488-1456
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C488-1456
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C488-1456 available by request