C488-1458 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-6-chloro-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine

C488-1458 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-6-chloro-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine
C488-1458 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-6-chloro-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound C488-1458
N-(2H-1,3-benzodioxol-5-yl)-6-chloro-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C488-1458

Molecular Formula

C21H16ClN3O2 (C21 H16 ClN3 O2)

Compound Name

N-(2H-1,3-benzodioxol-5-yl)-6-chloro-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-amine

IUPAC name

N-(2H-13-benzodioxol-5-yl)-6-chloro-2-(4-methylphenyl)imidazo[12-a]pyridin-3-amine

SMILES

Cc(cc1)ccc1-c1c(Nc(cc2)cc3c2OCO3)n(cc(cc2)Cl)c2n1

InChI

InChI=1S/C21H16ClN3O2/c1-13-2-4-14(5-3-13)20-21(25-11-15(22)6-9-19(25)24-20)23-16-7-8-17-18(10-16)27-12-26-17/h2-11,23H,12H2,1H3

InChI Key

BOULGNURQFVESQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682685

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.83

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.678

Distribution Coefficient, logD

5.661

Water Solubility, LogSw

-6.10

Polar Surface Area

34.687

Acid Dissociation Constant (pKa)

18.81

Base Dissociation Constant (pKb)

6.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

C488-1458 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
Targets:
  • Others

References: we are preparing a list of scientific research reports with C488-1458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C488-1458?
Check Price and Availability of C488-1458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C488-1458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C488-1458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C488-1458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C488-1458 available by request