C488-1461 Screening compound: 4-{3-[(2H-1,3-benzodioxol-5-yl)amino]-6-chloroimidazo[1,2-a]pyridin-2-yl}phenol

C488-1461 Screening compound: 4-{3-[(2H-1,3-benzodioxol-5-yl)amino]-6-chloroimidazo[1,2-a]pyridin-2-yl}phenol
C488-1461 Screening compound: 4-{3-[(2H-1,3-benzodioxol-5-yl)amino]-6-chloroimidazo[1,2-a]pyridin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C488-1461
4-{3-[(2H-1,3-benzodioxol-5-yl)amino]-6-chloroimidazo[1,2-a]pyridin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C488-1461

Molecular Formula

C20H14ClN3O3 (C20 H14 ClN3 O3)

Compound Name

4-{3-[(2H-1,3-benzodioxol-5-yl)amino]-6-chloroimidazo[1,2-a]pyridin-2-yl}phenol

IUPAC name

4-{3-[(2H-13-benzodioxol-5-yl)amino]-6-chloroimidazo[12-a]pyridin-2-yl}phenol

SMILES

Oc(cc1)ccc1-c1c(Nc(cc2)cc3c2OCO3)n(cc(cc2)Cl)c2n1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.8

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.634

Distribution Coefficient, logD

4.627

Water Solubility, LogSw

-4.66

Polar Surface Area

52.304

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

C488-1461 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with C488-1461 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C488-1461?
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What is the minimum amount of C488-1461 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C488-1461
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C488-1461
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C488-1461 available by request