C528-0501 Screening compound: 2-{[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]methanesulfonyl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
Chemical Structure Depiction of ChemDiv screening compound C528-0501
2-{[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]methanesulfonyl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
C528-0501
Molecular Formula
C23H24N2O4S (C23 H24 N2 O4 S)
Compound Name
2-{[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]methanesulfonyl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
IUPAC name
2-{[5-methyl-2-(4-methylphenyl)-13-oxazol-4-yl]methanesulfonyl}-1-(1234-tetrahydroisoquinolin-2-yl)ethan-1-one
SMILES
Cc1c(CS(CC(N(CC2)Cc3c2cccc3)=O)(=O)=O)nc(-c2ccc(C)cc2)o1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
424.52
Hydrogen Bond Acceptors Count
8.00
Hydrogen Bond Donors Count
0.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
3.309
Distribution Coefficient, logD
3.309
Water Solubility, LogSw
-3.50
Polar Surface Area
62.443
Acid Dissociation Constant (pKa)
13.07
Base Dissociation Constant (pKb)
-3.43
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
30.40
C528-0501 in Drug Discovery
Included in Screening Libraries
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
CNS targets activity set (6557 compounds)
Human GPCR Annotated Library (5539 compounds)
Human Ion Channels Annotated Library (353 compounds)
Human Transcription Factors Annotated Library (5098 compounds)
Selective Target Activity Profiling Library (14702 compounds)
ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)
Included in 1.7M Stock Database
References: we are preparing a list of scientific research reports with C528-0501 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)