C540-0130 Screening compound: 1-(3-chlorophenyl)-4-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperazine

C540-0130 Screening compound: 1-(3-chlorophenyl)-4-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperazine
C540-0130 Screening compound: 1-(3-chlorophenyl)-4-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound C540-0130
1-(3-chlorophenyl)-4-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C540-0130

Molecular Formula

C23H20ClFN4OS (C23 H20 ClFN4 OS)

Compound Name

1-(3-chlorophenyl)-4-[6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carbonyl]piperazine

IUPAC name

1-(3-chlorophenyl)-4-[6-(4-fluorophenyl)-3-methylimidazo[21-b][13]thiazole-2-carbonyl]piperazine

SMILES

Cc1c(C(N(CC2)CCN2c2cccc(Cl)c2)=O)sc2nc(-c(cc3)ccc3F)cn12

InChI

InChI=1S/C23H20ClFN4OS/c1-15-21(31-23-26-20(14-29(15)23)16-5-7-18(25)8-6-16)22(30)28-11-9-27(10-12-28)19-4-2-3-17(24)13-19/h2-8,13-14H,9-12H2,1H3

InChI Key

BUAZNNBFOBOXIZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04468974

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.96

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.066

Distribution Coefficient, logD

5.065

Water Solubility, LogSw

-5.30

Polar Surface Area

29.350

Acid Dissociation Constant (pKa)

28.24

Base Dissociation Constant (pKb)

4.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

C540-0130 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C540-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C540-0130?
Check Price and Availability of C540-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C540-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C540-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C540-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C540-0130 available by request