C540-0179 Screening compound: 6-(4-fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide

C540-0179 Screening compound: 6-(4-fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
C540-0179 Screening compound: 6-(4-fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C540-0179
6-(4-fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C540-0179

Molecular Formula

C20H16FN3O2S (C20 H16 FN3 O2 S)

Compound Name

6-(4-fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide

IUPAC name

6-(4-fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[21-b][13]thiazole-2-carboxamide

SMILES

Cc1c(C(Nc(cccc2)c2OC)=O)sc2nc(-c(cc3)ccc3F)cn12

InChI

InChI=1S/C20H16FN3O2S/c1-12-18(19(25)22-15-5-3-4-6-17(15)26-2)27-20-23-16(11-24(12)20)13-7-9-14(21)10-8-13/h3-11H,1-2H3,(H,22,25)

InChI Key

PBPMJMCPZXFZJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04469010

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.415

Distribution Coefficient, logD

4.414

Water Solubility, LogSw

-4.29

Polar Surface Area

39.466

Acid Dissociation Constant (pKa)

10.27

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

C540-0179 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C540-0179 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C540-0179?
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What is the minimum amount of C540-0179 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C540-0179
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C540-0179
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C540-0179 available by request