C540-0283 Screening compound: N-(2-fluorophenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide

C540-0283 Screening compound: N-(2-fluorophenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
C540-0283 Screening compound: N-(2-fluorophenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C540-0283
N-(2-fluorophenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C540-0283

Molecular Formula

C20H16FN3O2S (C20 H16 FN3 O2 S)

Compound Name

N-(2-fluorophenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide

IUPAC name

N-(2-fluorophenyl)-6-(4-methoxyphenyl)-3-methylimidazo[21-b][13]thiazole-2-carboxamide

SMILES

Cc1c(C(Nc(cccc2)c2F)=O)sc2nc(-c(cc3)ccc3OC)cn12

InChI

InChI=1S/C20H16FN3O2S/c1-12-18(19(25)22-16-6-4-3-5-15(16)21)27-20-23-17(11-24(12)20)13-7-9-14(26-2)10-8-13/h3-11H,1-2H3,(H,22,25)

InChI Key

WSXIKBXHODJPOU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04469067

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.395

Distribution Coefficient, logD

4.394

Water Solubility, LogSw

-4.22

Polar Surface Area

39.379

Acid Dissociation Constant (pKa)

9.83

Base Dissociation Constant (pKb)

2.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

C540-0283 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C540-0283 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C540-0283?
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What is the minimum amount of C540-0283 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C540-0283
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C540-0283
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C540-0283 available by request