C614-0578 Screening compound: N-(4-fluorophenyl)-3-{3-[(4-methoxyphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}propanamide

C614-0578 Screening compound: N-(4-fluorophenyl)-3-{3-[(4-methoxyphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}propanamide
C614-0578 Screening compound: N-(4-fluorophenyl)-3-{3-[(4-methoxyphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C614-0578
N-(4-fluorophenyl)-3-{3-[(4-methoxyphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C614-0578

Molecular Formula

C23H21FN4O2 (C23 H21 FN4 O2)

Compound Name

N-(4-fluorophenyl)-3-{3-[(4-methoxyphenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}propanamide

IUPAC name

N-(4-fluorophenyl)-3-{3-[(4-methoxyphenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}propanamide

SMILES

COc1ccc(Cn2c(nccc3)c3nc2CCC(Nc(cc2)ccc2F)=O)cc1

InChI

InChI=1S/C23H21FN4O2/c1-30-19-10-4-16(5-11-19)15-28-21(27-20-3-2-14-25-23(20)28)12-13-22(29)26-18-8-6-17(24)7-9-18/h2-11,14H,12-13,15H2,1H3,(H,26,29)

InChI Key

FGNLWXPKEQPBIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14776236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.632

Distribution Coefficient, logD

3.632

Water Solubility, LogSw

-3.90

Polar Surface Area

51.471

Acid Dissociation Constant (pKa)

10.59

Base Dissociation Constant (pKb)

4.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

C614-0578 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C614-0578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C614-0578?
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What is the minimum amount of C614-0578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C614-0578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C614-0578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C614-0578 available by request