C614-5372 Screening compound: 1-(3-CHLORO-4-METHYLPHENYL)-N-(3-FLUOROPHENYL)-5-PIPERIDIN-4-YL-1H-PYRAZOLE-4-CARBOXAMIDE

C614-5372 Screening compound: 1-(3-CHLORO-4-METHYLPHENYL)-N-(3-FLUOROPHENYL)-5-PIPERIDIN-4-YL-1H-PYRAZOLE-4-CARBOXAMIDE
C614-5372 Screening compound: 1-(3-CHLORO-4-METHYLPHENYL)-N-(3-FLUOROPHENYL)-5-PIPERIDIN-4-YL-1H-PYRAZOLE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound C614-5372
1-(3-CHLORO-4-METHYLPHENYL)-N-(3-FLUOROPHENYL)-5-PIPERIDIN-4-YL-1H-PYRAZOLE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C614-5372

Molecular Formula

C22H22ClFN4O (C22 H22 ClFN4 O)

Compound Name

1-(3-CHLORO-4-METHYLPHENYL)-N-(3-FLUOROPHENYL)-5-PIPERIDIN-4-YL-1H-PYRAZOLE-4-CARBOXAMIDE

IUPAC name

n/a

SMILES

Cc(ccc(-n1ncc(C(Nc2cc(F)ccc2)=O)c1C1CCNCC1)c1)c1Cl

InChI

InChI=1S/C22H22ClFN4O/c1-14-5-6-18(12-20(14)23)28-21(15-7-9-25-10-8-15)19(13-26-28)22(29)27-17-4-2-3-16(24)11-17/h2-6,11-13,15,25H,7-10H2,1H3,(H,27,29)

InChI Key

KSZHAWWUUVQXMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14776547

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

412.89

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.980

Distribution Coefficient, logD

0.499

Water Solubility, LogSw

-4.36

Polar Surface Area

48.305

Acid Dissociation Constant (pKa)

9.59

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

C614-5372 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C614-5372 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C614-5372?
Check Price and Availability of C614-5372, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C614-5372 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C614-5372
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C614-5372
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C614-5372 available by request