C614-6159 Screening compound: N-(3-chloro-4-methylphenyl)-3-{3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}propanamide

C614-6159 Screening compound: N-(3-chloro-4-methylphenyl)-3-{3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}propanamide
C614-6159 Screening compound: N-(3-chloro-4-methylphenyl)-3-{3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C614-6159
N-(3-chloro-4-methylphenyl)-3-{3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C614-6159

Molecular Formula

C22H19ClN4O (C22 H19 ClN4 O)

Compound Name

N-(3-chloro-4-methylphenyl)-3-{3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl}propanamide

IUPAC name

N-(3-chloro-4-methylphenyl)-3-{3-phenyl-3H-imidazo[45-b]pyridin-2-yl}propanamide

SMILES

Cc(ccc(NC(CCc(n1-c2ccccc2)nc2c1nccc2)=O)c1)c1Cl

InChI

InChI=1S/C22H19ClN4O/c1-15-9-10-16(14-18(15)23)25-21(28)12-11-20-26-19-8-5-13-24-22(19)27(20)17-6-3-2-4-7-17/h2-10,13-14H,11-12H2,1H3,(H,25,28)

InChI Key

HIHKYEOZCFCQCR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14776841

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.87

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.683

Distribution Coefficient, logD

4.683

Water Solubility, LogSw

-4.77

Polar Surface Area

44.671

Acid Dissociation Constant (pKa)

10.38

Base Dissociation Constant (pKb)

3.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

C614-6159 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antiviral Annotated Library (21441 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Purinergic Library (3321 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • Kinases
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C614-6159 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C614-6159?
Check Price and Availability of C614-6159, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C614-6159 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C614-6159
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C614-6159
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C614-6159 available by request