C632-0251 Screening compound: 3-(4-bromophenyl)-6-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

C632-0251 Screening compound: 3-(4-bromophenyl)-6-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
C632-0251 Screening compound: 3-(4-bromophenyl)-6-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound C632-0251
3-(4-bromophenyl)-6-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C632-0251

Molecular Formula

C20H19BrN4O2 (C20 H19 BrN4 O2)

Compound Name

3-(4-bromophenyl)-6-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

3-(4-bromophenyl)-6-(4-phenylpiperazin-1-yl)-1234-tetrahydropyrimidine-24-dione

SMILES

O=C(C=C(N1)N(CC2)CCN2c2ccccc2)N(c(cc2)ccc2Br)C1=O

InChI

InChI=1S/C20H19BrN4O2/c21-15-6-8-17(9-7-15)25-19(26)14-18(22-20(25)27)24-12-10-23(11-13-24)16-4-2-1-3-5-16/h1-9,14H,10-13H2,(H,22,27)

InChI Key

SERNOVFFGYVYMA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04471921

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.376

Distribution Coefficient, logD

3.375

Water Solubility, LogSw

-3.50

Polar Surface Area

46.967

Acid Dissociation Constant (pKa)

9.88

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

C632-0251 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C632-0251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C632-0251?
Check Price and Availability of C632-0251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C632-0251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C632-0251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C632-0251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C632-0251 available by request