C636-2451 Screening compound: 6-(4-METHYLPHENYL)-3-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZO[1,5-C][1,3]THIAZOLE-5,7(6H,7AH)-DIONE

C636-2451 Screening compound: 6-(4-METHYLPHENYL)-3-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZO[1,5-C][1,3]THIAZOLE-5,7(6H,7AH)-DIONE
C636-2451 Screening compound: 6-(4-METHYLPHENYL)-3-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZO[1,5-C][1,3]THIAZOLE-5,7(6H,7AH)-DIONE alternative view

Chemical Structure Depiction of ChemDiv screening compound C636-2451
6-(4-METHYLPHENYL)-3-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZO[1,5-C][1,3]THIAZOLE-5,7(6H,7AH)-DIONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C636-2451

Molecular Formula

C19H15F3N2O2S (C19 H15 F3 N2 O2 S)

Compound Name

6-(4-METHYLPHENYL)-3-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZO[1,5-C][1,3]THIAZOLE-5,7(6H,7AH)-DIONE

IUPAC name

n/a

SMILES

Cc(cc1)ccc1N(C(C1N2C(c3ccc(C(F)(F)F)cc3)SC1)=O)C2=O

InChI

InChI=1S/C19H15F3N2O2S/c1-11-2-8-14(9-3-11)23-16(25)15-10-27-17(24(15)18(23)26)12-4-6-13(7-5-12)19(20,21)22/h2-9,15,17H,10H2,1H3

InChI Key

QPFVHNLSKYARRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05974847

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.122

Distribution Coefficient, logD

4.122

Water Solubility, LogSw

-4.19

Polar Surface Area

32.146

Acid Dissociation Constant (pKa)

12.00

Base Dissociation Constant (pKb)

-5.74

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

26.30

C636-2451 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Epigenetics Focused Set (26518 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with C636-2451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C636-2451?
Check Price and Availability of C636-2451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C636-2451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C636-2451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C636-2451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C636-2451 available by request