C638-0298 Screening compound: (2Z)-N-(4-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)-3-phenylprop-2-enamide

C638-0298 Screening compound: (2Z)-N-(4-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)-3-phenylprop-2-enamide
C638-0298 Screening compound: (2Z)-N-(4-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C638-0298
(2Z)-N-(4-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C638-0298

Molecular Formula

C21H16N4O (C21 H16 N4 O)

Compound Name

(2Z)-N-(4-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)-3-phenylprop-2-enamide

IUPAC name

(2Z)-N-(4-{imidazo[12-a]pyrimidin-2-yl}phenyl)-3-phenylprop-2-enamide

SMILES

O=C(/C=C\c1ccccc1)Nc(cc1)ccc1-c1cn(cccn2)c2n1

InChI

InChI=1S/C21H16N4O/c26-20(12-7-16-5-2-1-3-6-16)23-18-10-8-17(9-11-18)19-15-25-14-4-13-22-21(25)24-19/h1-15H,(H,23,26)

InChI Key

FGODVGHQJSQVFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05897870

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.579

Distribution Coefficient, logD

3.578

Water Solubility, LogSw

-3.53

Polar Surface Area

42.987

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

4.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

C638-0298 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • 3D
  • Fragments
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C638-0298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C638-0298?
Check Price and Availability of C638-0298, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C638-0298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C638-0298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C638-0298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C638-0298 available by request