C648-0448 Screening compound: 3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)-N-[2-(4-methylphenyl)ethyl]propanamide

C648-0448 Screening compound: 3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)-N-[2-(4-methylphenyl)ethyl]propanamide
C648-0448 Screening compound: 3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)-N-[2-(4-methylphenyl)ethyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C648-0448
3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)-N-[2-(4-methylphenyl)ethyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C648-0448

Molecular Formula

C22H26N4O5S (C22 H26 N4 O5 S)

Compound Name

3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)-N-[2-(4-methylphenyl)ethyl]propanamide

IUPAC name

3-(13-dimethyl-24-dioxo-1234-tetrahydroquinazoline-6-sulfonamido)-N-[2-(4-methylphenyl)ethyl]propanamide

SMILES

Cc1ccc(CCNC(CCNS(c(cc2)cc(C(N3C)=O)c2N(C)C3=O)(=O)=O)=O)cc1

InChI

InChI=1S/C22H26N4O5S/c1-15-4-6-16(7-5-15)10-12-23-20(27)11-13-24-32(30,31)17-8-9-19-18(14-17)21(28)26(3)22(29)25(19)2/h4-9,14,24H,10-13H2,1-3H3,(H,23,27)

InChI Key

QFZQQDONSKWFGE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14779276

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.54

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.646

Distribution Coefficient, logD

1.645

Water Solubility, LogSw

-2.84

Polar Surface Area

97.254

Acid Dissociation Constant (pKa)

10.66

Base Dissociation Constant (pKb)

-0.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

C648-0448 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Human Kinases Annotated Library (2415 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with C648-0448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C648-0448?
Check Price and Availability of C648-0448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C648-0448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C648-0448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C648-0448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C648-0448 available by request