C660-0931 Screening compound: 3-(3-chloro-4-fluorophenyl)-2-(8-hydroxyquinolin-2-yl)-1,3-thiazolidin-4-one

C660-0931 Screening compound: 3-(3-chloro-4-fluorophenyl)-2-(8-hydroxyquinolin-2-yl)-1,3-thiazolidin-4-one
C660-0931 Screening compound: 3-(3-chloro-4-fluorophenyl)-2-(8-hydroxyquinolin-2-yl)-1,3-thiazolidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C660-0931
3-(3-chloro-4-fluorophenyl)-2-(8-hydroxyquinolin-2-yl)-1,3-thiazolidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C660-0931

Molecular Formula

C18H12ClFN2O2S (C18 H12 ClFN2 O2 S)

Compound Name

3-(3-chloro-4-fluorophenyl)-2-(8-hydroxyquinolin-2-yl)-1,3-thiazolidin-4-one

IUPAC name

3-(3-chloro-4-fluorophenyl)-2-(8-hydroxyquinolin-2-yl)-13-thiazolidin-4-one

SMILES

Oc1c2nc(C(N3c(cc4)cc(Cl)c4F)SCC3=O)ccc2ccc1

InChI

InChI=1S/C18H12ClFN2O2S/c19-12-8-11(5-6-13(12)20)22-16(24)9-25-18(22)14-7-4-10-2-1-3-15(23)17(10)21-14/h1-8,18,23H,9H2/t18-/m0/s1

InChI Key

JVECMMJIOHZJCQ-SFHVURJKSA-N

MDL Number (MFCD)

MFCD14780365

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.963

Distribution Coefficient, logD

3.957

Water Solubility, LogSw

-3.94

Polar Surface Area

41.782

Acid Dissociation Constant (pKa)

9.23

Base Dissociation Constant (pKb)

1.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.10

C660-0931 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Agro:
  • Agro
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C660-0931 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C660-0931?
Check Price and Availability of C660-0931, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C660-0931 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C660-0931
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C660-0931
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C660-0931 available by request