C724-0432 Screening compound: N-[(4-methylphenyl)methyl]-2-({4-oxo-3-phenyl-3H,4H-pyrido[2,3-d]pyrimidin-2-yl}sulfanyl)butanamide

C724-0432 Screening compound: N-[(4-methylphenyl)methyl]-2-({4-oxo-3-phenyl-3H,4H-pyrido[2,3-d]pyrimidin-2-yl}sulfanyl)butanamide
C724-0432 Screening compound: N-[(4-methylphenyl)methyl]-2-({4-oxo-3-phenyl-3H,4H-pyrido[2,3-d]pyrimidin-2-yl}sulfanyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C724-0432
N-[(4-methylphenyl)methyl]-2-({4-oxo-3-phenyl-3H,4H-pyrido[2,3-d]pyrimidin-2-yl}sulfanyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C724-0432

Molecular Formula

C25H24N4O2S (C25 H24 N4 O2 S)

Compound Name

N-[(4-methylphenyl)methyl]-2-({4-oxo-3-phenyl-3H,4H-pyrido[2,3-d]pyrimidin-2-yl}sulfanyl)butanamide

IUPAC name

N-[(4-methylphenyl)methyl]-2-({4-oxo-3-phenyl-3H4H-pyrido[23-d]pyrimidin-2-yl}sulfanyl)butanamide

SMILES

CCC(C(NCc1ccc(C)cc1)=O)SC(N1c2ccccc2)=Nc2ncccc2C1=O

InChI

InChI=1S/C25H24N4O2S/c1-3-21(23(30)27-16-18-13-11-17(2)12-14-18)32-25-28-22-20(10-7-15-26-22)24(31)29(25)19-8-5-4-6-9-19/h4-15,21H,3,16H2,1-2H3,(H,27,30)/t21-/m0/s1

InChI Key

VWJAMBCWOKVMHF-NRFANRHFSA-N

MDL Number (MFCD)

MFCD14788224

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.022

Distribution Coefficient, logD

4.022

Water Solubility, LogSw

-4.12

Polar Surface Area

59.468

Acid Dissociation Constant (pKa)

13.15

Base Dissociation Constant (pKb)

4.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

C724-0432 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C724-0432 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C724-0432?
Check Price and Availability of C724-0432, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C724-0432 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C724-0432
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C724-0432
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C724-0432 available by request