C734-0673 Screening compound: N-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-2-{1H,4H-chromeno[4,3-c]pyrazol-1-yl}acetamide

C734-0673 Screening compound: N-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-2-{1H,4H-chromeno[4,3-c]pyrazol-1-yl}acetamide
C734-0673 Screening compound: N-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-2-{1H,4H-chromeno[4,3-c]pyrazol-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C734-0673
N-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-2-{1H,4H-chromeno[4,3-c]pyrazol-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C734-0673

Molecular Formula

C21H15ClN4O3 (C21 H15 ClN4 O3)

Compound Name

N-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-2-{1H,4H-chromeno[4,3-c]pyrazol-1-yl}acetamide

IUPAC name

N-[3-(3-chlorophenyl)-12-oxazol-5-yl]-2-{1H4H-chromeno[43-c]pyrazol-1-yl}acetamide

SMILES

O=C(Cn1ncc2c1-c(cccc1)c1OC2)Nc1cc(-c2cccc(Cl)c2)no1

InChI

InChI=1S/C21H15ClN4O3/c22-15-5-3-4-13(8-15)17-9-20(29-25-17)24-19(27)11-26-21-14(10-23-26)12-28-18-7-2-1-6-16(18)21/h1-10H,11-12H2,(H,24,27)

InChI Key

SYUXMHANWLHFLP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14789726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.83

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.953

Distribution Coefficient, logD

3.953

Water Solubility, LogSw

-4.39

Polar Surface Area

67.337

Acid Dissociation Constant (pKa)

10.83

Base Dissociation Constant (pKb)

-3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

C734-0673 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C734-0673 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C734-0673?
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What is the minimum amount of C734-0673 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C734-0673
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C734-0673
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C734-0673 available by request