C736-0289 Screening compound: N-[(4-methylphenyl)methyl]-2-(pyridin-4-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine

C736-0289 Screening compound: N-[(4-methylphenyl)methyl]-2-(pyridin-4-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
C736-0289 Screening compound: N-[(4-methylphenyl)methyl]-2-(pyridin-4-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound C736-0289
N-[(4-methylphenyl)methyl]-2-(pyridin-4-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C736-0289

Molecular Formula

C22H18N6 (C22 H18 N6)

Compound Name

N-[(4-methylphenyl)methyl]-2-(pyridin-4-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine

IUPAC name

N-[(4-methylphenyl)methyl]-2-(pyridin-4-yl)-[124]triazolo[15-c]quinazolin-5-amine

SMILES

Cc1ccc(CNc2nc(cccc3)c3c3nc(-c4ccncc4)nn23)cc1

InChI

InChI=1S/C22H18N6/c1-15-6-8-16(9-7-15)14-24-22-25-19-5-3-2-4-18(19)21-26-20(27-28(21)22)17-10-12-23-13-11-17/h2-13H,14H2,1H3,(H,24,25)

InChI Key

ZBMZTOPGVGXKOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14789972

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.020

Distribution Coefficient, logD

3.933

Water Solubility, LogSw

-4.05

Polar Surface Area

51.057

Acid Dissociation Constant (pKa)

17.97

Base Dissociation Constant (pKb)

6.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

C736-0289 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C736-0289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C736-0289?
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What is the minimum amount of C736-0289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C736-0289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C736-0289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C736-0289 available by request