C762-0259 Screening compound: 2-{8-methyl-1H,4H-chromeno[4,3-c]pyrazol-1-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one

C762-0259 Screening compound: 2-{8-methyl-1H,4H-chromeno[4,3-c]pyrazol-1-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
C762-0259 Screening compound: 2-{8-methyl-1H,4H-chromeno[4,3-c]pyrazol-1-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound C762-0259
2-{8-methyl-1H,4H-chromeno[4,3-c]pyrazol-1-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C762-0259

Molecular Formula

C22H21N3O2 (C22 H21 N3 O2)

Compound Name

2-{8-methyl-1H,4H-chromeno[4,3-c]pyrazol-1-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one

IUPAC name

2-{8-methyl-1H4H-chromeno[43-c]pyrazol-1-yl}-1-(1234-tetrahydroisoquinolin-2-yl)ethan-1-one

SMILES

Cc(cc1)cc-2c1OCc1c2n(CC(N(CC2)Cc3c2cccc3)=O)nc1

InChI

InChI=1S/C22H21N3O2/c1-15-6-7-20-19(10-15)22-18(14-27-20)11-23-25(22)13-21(26)24-9-8-16-4-2-3-5-17(16)12-24/h2-7,10-11H,8-9,12-14H2,1H3

InChI Key

ZGNSTWGKRUAXRF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14792297

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.076

Distribution Coefficient, logD

3.076

Water Solubility, LogSw

-3.06

Polar Surface Area

37.961

Acid Dissociation Constant (pKa)

20.72

Base Dissociation Constant (pKb)

-1.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

C762-0259 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Therapeutical areas:
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic

References: we are preparing a list of scientific research reports with C762-0259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C762-0259?
Check Price and Availability of C762-0259, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C762-0259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C762-0259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C762-0259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C762-0259 available by request