C862-1520 Screening compound: 2-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-1-yl}-N-[(pyridin-2-yl)methyl]acetamide

C862-1520 Screening compound: 2-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-1-yl}-N-[(pyridin-2-yl)methyl]acetamide
C862-1520 Screening compound: 2-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-1-yl}-N-[(pyridin-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C862-1520
2-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-1-yl}-N-[(pyridin-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C862-1520

Molecular Formula

C17H18N4O2S (C17 H18 N4 O2 S)

Compound Name

2-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-1-yl}-N-[(pyridin-2-yl)methyl]acetamide

IUPAC name

2-{68-dimethyl-2-oxo-1H2H3H-pyrido[23-b][14]thiazin-1-yl}-N-[(pyridin-2-yl)methyl]acetamide

SMILES

Cc(cc(C)nc1SC2)c1N(CC(NCc1ncccc1)=O)C2=O

InChI

InChI=1S/C17H18N4O2S/c1-11-7-12(2)20-17-16(11)21(15(23)10-24-17)9-14(22)19-8-13-5-3-4-6-18-13/h3-7H,8-10H2,1-2H3,(H,19,22)

InChI Key

ZGJUZNKXNAPSFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14801880

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

342.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.646

Distribution Coefficient, logD

1.641

Water Solubility, LogSw

-2.48

Polar Surface Area

61.218

Acid Dissociation Constant (pKa)

12.77

Base Dissociation Constant (pKb)

5.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

C862-1520 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with C862-1520 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of C862-1520 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C862-1520
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C862-1520
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C862-1520 available by request