C999-1223 Screening compound: N-[2-(4-chlorophenyl)ethyl]-3-[3-(2-methoxyphenyl)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl]propanamide

C999-1223 Screening compound: N-[2-(4-chlorophenyl)ethyl]-3-[3-(2-methoxyphenyl)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl]propanamide
C999-1223 Screening compound: N-[2-(4-chlorophenyl)ethyl]-3-[3-(2-methoxyphenyl)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C999-1223
N-[2-(4-chlorophenyl)ethyl]-3-[3-(2-methoxyphenyl)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C999-1223

Molecular Formula

C26H27ClN4O2 (C26 H27 ClN4 O2)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-3-[3-(2-methoxyphenyl)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl]propanamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-3-[3-(2-methoxyphenyl)-46-dimethyl-1H-pyrazolo[34-b]pyridin-1-yl]propanamide

SMILES

Cc1c(c(-c(cccc2)c2OC)nn2CCC(NCCc(cc3)ccc3Cl)=O)c2nc(C)c1

InChI

InChI=1S/C26H27ClN4O2/c1-17-16-18(2)29-26-24(17)25(21-6-4-5-7-22(21)33-3)30-31(26)15-13-23(32)28-14-12-19-8-10-20(27)11-9-19/h4-11,16H,12-15H2,1-3H3,(H,28,32)

InChI Key

JVJHMAUEMIFMLO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14810145

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.084

Distribution Coefficient, logD

4.084

Water Solubility, LogSw

-4.50

Polar Surface Area

55.148

Acid Dissociation Constant (pKa)

14.18

Base Dissociation Constant (pKb)

2.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

C999-1223 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with C999-1223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C999-1223?
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What is the minimum amount of C999-1223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C999-1223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C999-1223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C999-1223 available by request