CM1461-2337 Screening compound: 1-methyl-3-[(4-methylpiperazino)methyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl (2,3,5,6-tetramethylphenyl) sulfone

CM1461-2337 Screening compound: 1-methyl-3-[(4-methylpiperazino)methyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl (2,3,5,6-tetramethylphenyl) sulfone
CM1461-2337 Screening compound: 1-methyl-3-[(4-methylpiperazino)methyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl (2,3,5,6-tetramethylphenyl) sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound CM1461-2337
1-methyl-3-[(4-methylpiperazino)methyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl (2,3,5,6-tetramethylphenyl) sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM1461-2337

Molecular Formula

C23H35N5O2S (C23 H35 N5 O2 S)

Compound Name

1-methyl-3-[(4-methylpiperazino)methyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl (2,3,5,6-tetramethylphenyl) sulfone

IUPAC name

1-methyl-4-{[1-methyl-5-(2356-tetramethylbenzenesulfonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]methyl}piperazine

SMILES

Cc1c(C)c(S(N(CC2)Cc3c2n(C)nc3CN2CCN(C)CC2)(=O)=O)c(C)c(C)c1

InChI

InChI=1S/C23H35N5O2S/c1-16-13-17(2)19(4)23(18(16)3)31(29,30)28-8-7-22-20(14-28)21(24-26(22)6)15-27-11-9-25(5)10-12-27/h13H,7-12,14-15H2,1-6H3

InChI Key

VTENJMXGCWWVDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30458421

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.463

Distribution Coefficient, logD

-1.253

Water Solubility, LogSw

-2.37

Polar Surface Area

54.333

Acid Dissociation Constant (pKa)

22.23

Base Dissociation Constant (pKb)

11.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.87

CM1461-2337 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with CM1461-2337 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM1461-2337?
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What is the minimum amount of CM1461-2337 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM1461-2337
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM1461-2337
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM1461-2337 available by request