CM1461-4244 Screening compound: N-({1,5-dimethyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}methyl)-6-methoxypyridine-3-carboxamide

CM1461-4244 Screening compound: N-({1,5-dimethyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}methyl)-6-methoxypyridine-3-carboxamide
CM1461-4244 Screening compound: N-({1,5-dimethyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}methyl)-6-methoxypyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound CM1461-4244
N-({1,5-dimethyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}methyl)-6-methoxypyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM1461-4244

Molecular Formula

C16H21N5O2 (C16 H21 N5 O2)

Compound Name

N-({1,5-dimethyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl}methyl)-6-methoxypyridine-3-carboxamide

IUPAC name

N-({15-dimethyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl}methyl)-6-methoxypyridine-3-carboxamide

SMILES

Cn1nc(CNC(c(cc2)cnc2OC)=O)c2c1CCN(C)C2

InChI

InChI=1S/C16H21N5O2/c1-20-7-6-14-12(10-20)13(19-21(14)2)9-18-16(22)11-4-5-15(23-3)17-8-11/h4-5,8H,6-7,9-10H2,1-3H3,(H,18,22)

InChI Key

VDJOSCUVUNOBJR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30460185

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.392

Distribution Coefficient, logD

-5.829

Water Solubility, LogSw

-1.78

Polar Surface Area

60.077

Acid Dissociation Constant (pKa)

12.25

Base Dissociation Constant (pKb)

13.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.75

CM1461-4244 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

CNS Targets (44014 compounds)

Soluble Diversity Library (15920 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with CM1461-4244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM1461-4244?
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What is the minimum amount of CM1461-4244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM1461-4244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM1461-4244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM1461-4244 available by request