CM1461-7374 Screening compound: 2-(1H-indol-3-yl)-N~1~-{[1-methyl-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]methyl}acetamide

CM1461-7374 Screening compound: 2-(1H-indol-3-yl)-N~1~-{[1-methyl-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]methyl}acetamide
CM1461-7374 Screening compound: 2-(1H-indol-3-yl)-N~1~-{[1-methyl-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]methyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound CM1461-7374
2-(1H-indol-3-yl)-N~1~-{[1-methyl-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]methyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM1461-7374

Molecular Formula

C19H23N5O3S (C19 H23 N5 O3 S)

Compound Name

2-(1H-indol-3-yl)-N~1~-{[1-methyl-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]methyl}acetamide

IUPAC name

n/a

SMILES

Cn1nc(CNC(Cc2c[nH]c3c2cccc3)=O)c(C2)c1CCN2S(C)(=O)=O

InChI

InChI=1S/C19H23N5O3S/c1-23-18-7-8-24(28(2,26)27)12-15(18)17(22-23)11-21-19(25)9-13-10-20-16-6-4-3-5-14(13)16/h3-6,10,20H,7-9,11-12H2,1-2H3,(H,21,25)

InChI Key

DAGNCVUEAKCTFI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30458460

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.815

Distribution Coefficient, logD

0.815

Water Solubility, LogSw

-2.28

Polar Surface Area

80.959

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

0.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

CM1461-7374 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with CM1461-7374 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM1461-7374?
Check Price and Availability of CM1461-7374, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM1461-7374 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM1461-7374
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM1461-7374
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM1461-7374 available by request