CM2346-0426 Screening compound: 2,6-difluoro-N-({2-methyl-2-azaspiro[4.5]decan-4-yl}methyl)benzamide

CM2346-0426 Screening compound: 2,6-difluoro-N-({2-methyl-2-azaspiro[4.5]decan-4-yl}methyl)benzamide
CM2346-0426 Screening compound: 2,6-difluoro-N-({2-methyl-2-azaspiro[4.5]decan-4-yl}methyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound CM2346-0426
2,6-difluoro-N-({2-methyl-2-azaspiro[4.5]decan-4-yl}methyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM2346-0426

Molecular Formula

C18H24F2N2O (C18 H24 F2 N2 O)

Compound Name

2,6-difluoro-N-({2-methyl-2-azaspiro[4.5]decan-4-yl}methyl)benzamide

IUPAC name

26-difluoro-N-({2-methyl-2-azaspiro[4.5]decan-4-yl}methyl)benzamide

SMILES

CN1CC2(CCCCC2)C(CNC(c(c(F)ccc2)c2F)=O)C1

InChI

InChI=1S/C18H24F2N2O/c1-22-11-13(18(12-22)8-3-2-4-9-18)10-21-17(23)16-14(19)6-5-7-15(16)20/h5-7,13H,2-4,8-12H2,1H3,(H,21,23)/t13-/m0/s1

InChI Key

KRPRVTGTICSUFC-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD30458572

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.4

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.773

Distribution Coefficient, logD

-1.314

Water Solubility, LogSw

-3.02

Polar Surface Area

28.474

Acid Dissociation Constant (pKa)

10.75

Base Dissociation Constant (pKb)

11.14

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.11

CM2346-0426 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with CM2346-0426 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM2346-0426?
Check Price and Availability of CM2346-0426, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM2346-0426 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM2346-0426
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM2346-0426
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM2346-0426 available by request