CM2346-1702 Screening compound: 3-{[2-(cyclopropylmethyl)-2-azaspiro[4.5]decan-4-yl]methyl}-1-(4-ethoxyphenyl)urea

CM2346-1702 Screening compound: 3-{[2-(cyclopropylmethyl)-2-azaspiro[4.5]decan-4-yl]methyl}-1-(4-ethoxyphenyl)urea
CM2346-1702 Screening compound: 3-{[2-(cyclopropylmethyl)-2-azaspiro[4.5]decan-4-yl]methyl}-1-(4-ethoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound CM2346-1702
3-{[2-(cyclopropylmethyl)-2-azaspiro[4.5]decan-4-yl]methyl}-1-(4-ethoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM2346-1702

Molecular Formula

C23H35N3O2 (C23 H35 N3 O2)

Compound Name

3-{[2-(cyclopropylmethyl)-2-azaspiro[4.5]decan-4-yl]methyl}-1-(4-ethoxyphenyl)urea

IUPAC name

3-{[2-(cyclopropylmethyl)-2-azaspiro[4.5]decan-4-yl]methyl}-1-(4-ethoxyphenyl)urea

SMILES

CCOc(cc1)ccc1NC(NCC(CN(CC1CC1)C1)C11CCCCC1)=O

InChI

InChI=1S/C23H35N3O2/c1-2-28-21-10-8-20(9-11-21)25-22(27)24-14-19-16-26(15-18-6-7-18)17-23(19)12-4-3-5-13-23/h8-11,18-19H,2-7,12-17H2,1H3,(H2,24,25,27)/t19-/m0/s1

InChI Key

GALUBYXNVAMCHH-IBGZPJMESA-N

MDL Number (MFCD)

MFCD30458601

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.415

Distribution Coefficient, logD

-0.947

Water Solubility, LogSw

-3.98

Polar Surface Area

45.396

Acid Dissociation Constant (pKa)

13.49

Base Dissociation Constant (pKb)

12.76

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

69.57

CM2346-1702 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with CM2346-1702 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM2346-1702?
Check Price and Availability of CM2346-1702, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM2346-1702 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM2346-1702
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM2346-1702
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM2346-1702 available by request