CM3473-1099 Screening compound: 1'-(3,5-difluorobenzenesulfonyl)-7-methyl-6,7-dihydro-5H-spiro[imidazo[1,2-a]pyrazine-8,4'-piperidine]

CM3473-1099 Screening compound: 1'-(3,5-difluorobenzenesulfonyl)-7-methyl-6,7-dihydro-5H-spiro[imidazo[1,2-a]pyrazine-8,4'-piperidine]
CM3473-1099 Screening compound: 1'-(3,5-difluorobenzenesulfonyl)-7-methyl-6,7-dihydro-5H-spiro[imidazo[1,2-a]pyrazine-8,4'-piperidine] alternative view

Chemical Structure Depiction of ChemDiv screening compound CM3473-1099
1'-(3,5-difluorobenzenesulfonyl)-7-methyl-6,7-dihydro-5H-spiro[imidazo[1,2-a]pyrazine-8,4'-piperidine]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM3473-1099

Molecular Formula

C17H20F2N4O2S (C17 H20 F2 N4 O2 S)

Compound Name

1'-(3,5-difluorobenzenesulfonyl)-7-methyl-6,7-dihydro-5H-spiro[imidazo[1,2-a]pyrazine-8,4'-piperidine]

IUPAC name

1'-(35-difluorobenzenesulfonyl)-7-methyl-67-dihydro-5H-spiro[imidazo[12-a]pyrazine-84'-piperidine]

SMILES

CN1C(CC2)(CCN2S(c2cc(F)cc(F)c2)(=O)=O)c2nccn2CC1

InChI

InChI=1S/C17H20F2N4O2S/c1-21-8-9-22-7-4-20-16(22)17(21)2-5-23(6-3-17)26(24,25)15-11-13(18)10-14(19)12-15/h4,7,10-12H,2-3,5-6,8-9H2,1H3

InChI Key

DWDKTDFLWPIRHI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30459821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.116

Distribution Coefficient, logD

-0.638

Water Solubility, LogSw

-2.26

Polar Surface Area

47.106

Acid Dissociation Constant (pKa)

26.03

Base Dissociation Constant (pKb)

10.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.06

CM3473-1099 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with CM3473-1099 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM3473-1099?
Check Price and Availability of CM3473-1099, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM3473-1099 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM3473-1099
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM3473-1099
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM3473-1099 available by request